Cambridge-based fragment-based drug discovery (Otsuka group); structural biology and oncology pipeline.
More about Astex Pharmaceuticals
Astex Pharmaceuticals is a biotechnology company dedicated to discovering and developing small-molecule therapeutics for oncology and central nervous system diseases. Founded in 1999 in Cambridge, England, it is now a wholly owned subsidiary of Otsuka Pharmaceutical Co., Ltd. The company operates from the Cambridge Science Park, where it focuses on fragment-based drug discovery through its proprietary platform, Pyramid. Astex has developed a robust pipeline of novel therapies, including three approved oncology drugs: Kisqali® (with Novartis), Balversa® (with Janssen), and Truqap™ (from AstraZeneca). Its investigational products include SGI-110, AT13387, AT7519, and Amuvatinib, targeting various cancers. The company collaborates with major pharmaceutical partners like Novartis, AstraZeneca, and Merck to advance additional compounds into clinical trials. Astex is committed to addressing high unmet medical needs in patient populations affected by cancer and neurodegenerative diseases.
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